Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice

HDAC inhibitors (HDACi) exert beneficial effects in mdx mice, by promoting endogenous regeneration; however, the cellular determinants of HDACi activity on dystrophic muscles have not been determined. We show that fibroadipogenic progenitors (FAP) influence the regeneration potential of satellite ce...

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Detalles Bibliográficos
Autores principales: Mozzetta, Chiara, Consalvi, Silvia, Saccone, Valentina, Tierney, Matthew, Diamantini, Adamo, Mitchell, Kathryn J, Marazzi, Giovanna, Borsellino, Giovanna, Battistini, Luca, Sassoon, David, Sacco, Alessandra, Puri, Pier Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628105/
https://www.ncbi.nlm.nih.gov/pubmed/23505062
http://dx.doi.org/10.1002/emmm.201202096

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