Thrombospondin-1 Signaling through CD47 Inhibits Self-renewal by Regulating c-Myc and Other Stem Cell Transcription Factors

Signaling through the thrombospondin-1 receptor CD47 broadly limits cell and tissue survival of stress, but the molecular mechanisms are incompletely understood. We now show that loss of CD47 permits sustained proliferation of primary murine endothelial cells, increases asymmetric division, and enab...

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Detalles Bibliográficos
Autores principales: Kaur, Sukhbir, Soto-Pantoja, David R., Stein, Erica V., Liu, Chengyu, Elkahloun, Abdel G., Pendrak, Michael L., Nicolae, Alina, Singh, Satya P., Nie, Zuqin, Levens, David, Isenberg, Jeffrey S., Roberts, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628113/
https://www.ncbi.nlm.nih.gov/pubmed/23591719
http://dx.doi.org/10.1038/srep01673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628113/
https://www.ncbi.nlm.nih.gov/pubmed/23591719
http://dx.doi.org/10.1038/srep01673

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