Iodine-131 meta-iodobezylguanidine single photon emission computed tomography/computerized tomography in diagnosis of neuro-endocrine tumors

Metaiodobenzyl guanidine (MIBG) is a derivative of guanethidine and acts as an analogue of nor-epinephrine and is widely used in the imaging of tumors of neuro-endocrine origin. Iodine-123 MIBG has ideal imaging characteristics but is expensive with limited availability. Iodine-131 MIBG is widely us...

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Detalles Bibliográficos
Autores principales: Harisankar, Chidambaram Natrajan Balasubramanian, Mittal, Bhagwant Rai, Bhattacharya, Anish, Kashyap, Raghava, Bhansali, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Pictorial Essay
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628268/
https://www.ncbi.nlm.nih.gov/pubmed/23599604
http://dx.doi.org/10.4103/0972-3919.108877
Descripción
Sumario:Metaiodobenzyl guanidine (MIBG) is a derivative of guanethidine and acts as an analogue of nor-epinephrine and is widely used in the imaging of tumors of neuro-endocrine origin. Iodine-123 MIBG has ideal imaging characteristics but is expensive with limited availability. Iodine-131 MIBG is widely used in India and is cheap. Hybrid single photon emission computed tomography (SPECT)/computerized tomography (CT) allows for anatomico-functional imaging and is being tried in MIBG studies. However, the experience with I-131 MIBG is limited. We present a pictorial assay of I-131 MIBG SPECT/CT findings in various MIBG avid tumors.

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