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Extensive Alternative Splicing of the Repressor Element Silencing Transcription Factor Linked to Cancer

The repressor element silencing transcription factor (REST) is a coordinate transcriptional and epigenetic regulator which functions as a tumor suppressor or an oncogene depending on cellular context, and a truncated splice variant REST4 has been linked to various types of cancer. We performed a com...

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Detalles Bibliográficos
Autores principales: Chen, Guo-Lin, Miller, Gregory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628349/
https://www.ncbi.nlm.nih.gov/pubmed/23614038
http://dx.doi.org/10.1371/journal.pone.0062217