Paraquat Modulates Alternative Pre-mRNA Splicing by Modifying the Intracellular Distribution of SRPK2

Paraquat (PQ) is a neurotoxic herbicide that induces superoxide formation. Although it is known that its toxic properties are linked to ROS production, the cellular response to PQ is still poorly understood. We reported previously that treatment with PQ induced genome-wide changes in pre-mRNA splici...

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Detalles Bibliográficos
Autores principales: Vivarelli, Silvia, Lenzken, Silvia C., Ruepp, Marc-David, Ranzini, Francesco, Maffioletti, Andrea, Alvarez, Reinaldo, Mühlemann, Oliver, Barabino, Silvia M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628584/
https://www.ncbi.nlm.nih.gov/pubmed/23613995
http://dx.doi.org/10.1371/journal.pone.0061980

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