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Contribution of NMDA Receptor Hypofunction in Prefrontal and Cortical Excitatory Neurons to Schizophrenia-Like Phenotypes

Pharmacological and genetic studies support a role for NMDA receptor (NMDAR) hypofunction in the etiology of schizophrenia. We have previously demonstrated that NMDAR obligatory subunit 1 (GluN1) deletion in corticolimbic interneurons during early postnatal development is sufficient to confer schizo...

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Detalles Bibliográficos
Autores principales: Rompala, Gregory R., Zsiros, Veronika, Zhang, Shuqin, Kolata, Stefan M., Nakazawa, Kazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628715/
https://www.ncbi.nlm.nih.gov/pubmed/23613827
http://dx.doi.org/10.1371/journal.pone.0061278