The Relationship between RTS,S Vaccine-Induced Antibodies, CD4(+) T Cell Responses and Protection against Plasmodium falciparum Infection

Vaccination with the pre-erythrocytic malaria vaccine RTS,S induces high levels of antibodies and CD4(+) T cells specific for the circumsporozoite protein (CSP). Using a biologically-motivated mathematical model of sporozoite infection fitted to data from malaria-naive adults vaccinated with RTS,S a...

Descripción completa

Detalles Bibliográficos
Autores principales: White, Michael T., Bejon, Philip, Olotu, Ally, Griffin, Jamie T., Riley, Eleanor M., Kester, Kent E., Ockenhouse, Christian F., Ghani, Azra C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628884/
https://www.ncbi.nlm.nih.gov/pubmed/23613845
http://dx.doi.org/10.1371/journal.pone.0061395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628884/
https://www.ncbi.nlm.nih.gov/pubmed/23613845
http://dx.doi.org/10.1371/journal.pone.0061395

Ejemplares similares