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Early Vessel Destabilization Mediated by Angiopoietin-2 and Subsequent Vessel Maturation via Angiopoietin-1 Induce Functional Neovasculature after Ischemia

BACKGROUND: We assessed whether Angiopoietin-2 (Ang2), a Tie2 ligand and partial antagonist of Angiopoietin-1 (Ang1), is required for early vessel destabilization during postischemic angiogenesis, when combined with vascular growth factors. METHODS: In vitro, matrigel co-cultures assessed endothelia...

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Detalles Bibliográficos
Autores principales:	Qin, Di, Trenkwalder, Teresa, Lee, Seungmin, Chillo, Omary, Deindl, Elisabeth, Kupatt, Christian, Hinkel, Rabea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628915/ https://www.ncbi.nlm.nih.gov/pubmed/23613948 http://dx.doi.org/10.1371/journal.pone.0061831

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