Rac2-Deficiency Leads to Exacerbated and Protracted Colitis in Response to Citrobacter rodentium Infection

Recent genetic-based studies have implicated a number of immune-related genes in the pathogenesis of inflammatory bowel disease (IBD). Our recent genetic studies showed that RAC2 is associated with human IBD; however, its role in disease pathogenesis is unclear. Given Rac2’s importance in various fu...

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Detalles Bibliográficos
Autores principales: Fattouh, Ramzi, Guo, Cong-Hui, Lam, Grace Y., Gareau, Melanie G., Ngan, Bo-Yee, Glogauer, Michael, Muise, Aleixo M., Brumell, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628927/
https://www.ncbi.nlm.nih.gov/pubmed/23613889
http://dx.doi.org/10.1371/journal.pone.0061629

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