Comparability of Mixed IC(50) Data – A Statistical Analysis

The biochemical half maximal inhibitory concentration (IC(50)) is the most commonly used metric for on-target activity in lead optimization. It is used to guide lead optimization, build large-scale chemogenomics analysis, off-target activity and toxicity models based on public data. However, the use...

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Detalles Bibliográficos
Autores principales: Kalliokoski, Tuomo, Kramer, Christian, Vulpetti, Anna, Gedeck, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628986/
https://www.ncbi.nlm.nih.gov/pubmed/23613770
http://dx.doi.org/10.1371/journal.pone.0061007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628986/
https://www.ncbi.nlm.nih.gov/pubmed/23613770
http://dx.doi.org/10.1371/journal.pone.0061007

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