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Influenza Nucleoprotein Delivered with Aluminium Salts Protects Mice from an Influenza A Virus That Expresses an Altered Nucleoprotein Sequence

Influenza virus poses a difficult challenge for protective immunity. This virus is adept at altering its surface proteins, the proteins that are the targets of neutralizing antibody. Consequently, each year a new vaccine must be developed to combat the current recirculating strains. A universal infl...

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Detalles Bibliográficos
Autores principales: MacLeod, Megan K. L., David, Alexandria, Jin, Niyun, Noges, Laura, Wang, Jieru, Kappler, John W., Marrack, Philippa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629017/
https://www.ncbi.nlm.nih.gov/pubmed/23613928
http://dx.doi.org/10.1371/journal.pone.0061775