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Polymorphisms in thymidylate synthase and reduced folate carrier (SLC19A1) genes predict survival outcome in advanced non-small cell lung cancer patients treated with pemetrexed-based chemotherapy

The aim of this study was to evaluate the association between thymidylate synthase (TS), methylenetetrahydrofolate reductase (MTHFR) and reduced folate carrier (SLC19A1) gene polymorphisms and the treatment efficacy of pemetrexed-based chemotherapy in advanced non-small cell lung cancer (NSCLC). Adv...

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Detalles Bibliográficos
Autores principales: LI, WEN-JUAN, JIANG, HUA, FANG, XIN-JIAN, YE, HONG-LING, LIU, MING-HUAN, LIU, YAN-WEN, CHEN, QIAN, ZHANG, LI, ZHANG, JIN-YU, YUAN, CHUN-LUAN, ZHANG, QIU-YUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629022/
https://www.ncbi.nlm.nih.gov/pubmed/23599757
http://dx.doi.org/10.3892/ol.2013.1175