Cargando…

Huaier aqueous extract inhibits colorectal cancer stem cell growth partially via downregulation of the Wnt/β-catenin pathway

The existence of cancer stem cells (CSCs) is central to the pathogenesis and therapy resistance of colorectal cancer. The aim of this study was to evaluate whether Huaier aqueous extract, a Chinese medicine, has efficacy against CSCs and to investigate the mechanisms of its anticancer effects. It wa...

Descripción completa

Detalles Bibliográficos
Autores principales:	ZHANG, TAO, WANG, KE, ZHANG, JUNSHU, WANG, XIAOLEI, CHEN, ZHIGANG, NI, CHAO, QIU, FUMING, HUANG, JIAN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629070/ https://www.ncbi.nlm.nih.gov/pubmed/23599758 http://dx.doi.org/10.3892/ol.2013.1145

Ejemplares similares

Anti-angiogenic and antitumor activities of Huaier aqueous extract
por: WANG, XIAOLONG, et al.
Publicado: (2012)

Huaier Aqueous Extract Inhibits Ovarian Cancer Cell Motility via the AKT/GSK3β/β-Catenin Pathway
por: Yan, Xiaohui, et al.
Publicado: (2013)

Aqueous Huaier Extract Suppresses Gastric Cancer Metastasis and Epithelial to Mesenchymal Transition by Targeting Twist
por: Xu, Zhiyuan, et al.
Publicado: (2017)

Effects of Huaier Extract on Ameliorating Colitis-Associated Colorectal Tumorigenesis in Mice
por: Zou, Yi-feng, et al.
Publicado: (2020)

Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway
por: Zhang, Chengshuo, et al.
Publicado: (2015)

Huaier aqueous extract induces apoptosis of human fibrosarcoma HT1080 cells through the mitochondrial pathway
por: CUI, YANG, et al.
Publicado: (2015)

Aqueous extract of Sanguisorba officinalis blocks the Wnt/β-catenin signaling pathway in colorectal cancer cells
por: Liu, Meng-ping, et al.
Publicado: (2018)

Huaier Augmented the Chemotherapeutic Sensitivity of Oxaliplatin via Downregulation of YAP in Hepatocellular Carcinoma
por: Tao, Yuquan, et al.
Publicado: (2018)

Huaier aqueous extract protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NLRP3 inflammasome activation
por: Wang, Lijuan, et al.
Publicado: (2017)

GSTZ1‐1 downregulates Wnt/β‐catenin signalling in hepatocellular carcinoma cells
por: Lei, Chong, et al.
Publicado: (2019)

Huaier extract suppresses breast cancer via regulating tumor-associated macrophages
por: Li, Yaming, et al.
Publicado: (2016)

Anti-tumor effect of Huaier extract against neuroblastoma cells in vitro
por: Xu, Dong-qing, et al.
Publicado: (2021)

Novel micelle formulation of curcumin for enhancing antitumor activity and inhibiting colorectal cancer stem cells
por: Wang, Ke, et al.
Publicado: (2012)

Effect of Huaier on Melanoma Invasion, Metastasis, and Angiogenesis
por: Su, Dongqiang, et al.
Publicado: (2020)

Astragalus membranaceus (Huangqi) and Rhizoma curcumae (Ezhu) decoction suppresses colorectal cancer via downregulation of Wnt5/β-Catenin signal
por: Bian, Yong, et al.
Publicado: (2022)

Curcumin suppresses colorectal tumorigenesis via the Wnt/β-catenin signaling pathway by downregulating Axin2
por: Hao, Jiaxue, et al.
Publicado: (2021)

Effects of adjuvant huaier granule therapy on survival rate of patients with hepatocellular carcinoma
por: Shi, Ke, et al.
Publicado: (2023)

Huaier n-butanol extract suppresses proliferation and metastasis of gastric cancer via c-Myc-Bmi1 axis
por: Wang, Yiping, et al.
Publicado: (2019)

Huaier extract synergizes with tamoxifen to induce autophagy and apoptosis in ER-positive breast cancer cells
por: Qi, Wenwen, et al.
Publicado: (2016)

Effects of LDOC1 on colorectal cancer cells via downregulation of the Wnt/β-catenin signaling pathway
por: Jiang, Jiayi, et al.
Publicado: (2019)

Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus
por: Granno, Simone, et al.
Publicado: (2019)

ACY1 Downregulation Enhances the Radiosensitivity of Cetuximab-Resistant Colorectal Cancer by Inactivating the Wnt/β-Catenin Signaling Pathway
por: Shan, Wulin, et al.
Publicado: (2022)

NLRP12 downregulates the Wnt/β-catenin pathway via interaction with STK38 to suppress colorectal cancer
por: Khan, Shahanshah, et al.
Publicado: (2023)

Huaier Extract Induces Autophagic Cell Death by Inhibiting the mTOR/S6K Pathway in Breast Cancer Cells
por: Wang, Xiaolong, et al.
Publicado: (2015)

Huaier Suppresses the Hepatocellular Carcinoma Cell Cycle by Regulating Minichromosome Maintenance Proteins
por: Niu, Yongjie, et al.
Publicado: (2020)

Research Progress on the Anti-Cancer Molecular Mechanisms of Huaier
por: Qi, Tongtong, et al.
Publicado: (2020)

The synergistic antitumor effect of Huaier combined with 5-Florouracil in human cholangiocarcinoma cells
por: Fu, Zhaoyu, et al.
Publicado: (2019)

Wnt2 complements Wnt/β-catenin signaling in colorectal cancer
por: Jung, Youn-Sang, et al.
Publicado: (2015)

The oncogenic role of Wnt10a in colorectal cancer through activation of canonical Wnt/β-catenin signaling
por: Li, Jinlong, et al.
Publicado: (2019)

Downregulation of TET1 Promotes Glioma Cell Proliferation and Invasion by Targeting Wnt/β-Catenin Pathway
por: Ji, Jianwen, et al.
Publicado: (2021)

Targeting CDH17 Suppresses Tumor Progression in Gastric Cancer by Downregulating Wnt/β-Catenin Signaling
por: Qiu, Hai-bo, et al.
Publicado: (2013)

Huaier Restrains Proliferative and Migratory Potential of Hepatocellular Carcinoma Cells Partially Through Decreased Yes-Associated Protein 1
por: Shan, Liang, et al.
Publicado: (2017)

Huaier suppresses pancreatic cancer progression via activating cell autophagy induced ferroptosis
por: Zhu, Zeen, et al.
Publicado: (2022)

Huaier increases the antitumor effect of gemcitabine on pancreatic cancer in vitro and in vivo
por: Chen, Tao, et al.
Publicado: (2021)

Downregulation of miR-610 promotes proliferation and tumorigenicity and activates Wnt/β-catenin signaling in human hepatocellular carcinoma
por: Zeng, Xian-Cheng, et al.
Publicado: (2014)

Knockdown of BAP31 Downregulates Galectin-3 to Inhibit the Wnt/β-Catenin Signaling Pathway to Modulate 5-FU Chemosensitivity and Cancer Stemness in Colorectal Cancer
por: Liu, Jingjing, et al.
Publicado: (2023)

Inhibition of Dishevelled-2 suppresses the biological behavior of pancreatic cancer by downregulating Wnt/β-catenin signaling
por: Hu, Wei, et al.
Publicado: (2021)

Role of Wnt/β-Catenin Signaling in the Chemoresistance Modulation of Colorectal Cancer
por: Yuan, Shengli, et al.
Publicado: (2020)

Huaier Extract Inhibits Prostate Cancer Growth via Targeting AR/AR-V7 Pathway
por: Liu, Zhengfang, et al.
Publicado: (2021)

Correction: Targeting CDH17 Suppresses Tumor Progression in Gastric Cancer by Downregulating Wnt/β-Catenin Signaling
por: Qiu, Hai-bo, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_oqv097skthfr2mc036ilv2hsge