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Defining the Genomic Signature of Totipotency and Pluripotency during Early Human Development
The genetic mechanisms governing human pre-implantation embryo development and the in vitro counterparts, human embryonic stem cells (hESCs), still remain incomplete. Previous global genome studies demonstrated that totipotent blastomeres from day-3 human embryos and pluripotent inner cell masses (I...
Autores principales: | Galan, Amparo, Diaz-Gimeno, Patricia, Poo, Maria Eugenia, Valbuena, Diana, Sanchez, Eva, Ruiz, Veronica, Dopazo, Joaquin, Montaner, David, Conesa, Ana, Simon, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629124/ https://www.ncbi.nlm.nih.gov/pubmed/23614026 http://dx.doi.org/10.1371/journal.pone.0062135 |
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