Identification of Human Monoclonal Antibodies Specific for Human SOD1 Recognizing Distinct Epitopes and Forms of SOD1

Mutations in the gene encoding human SOD1 (hSOD1) can cause amyotrophic lateral sclerosis (ALS) yet the mechanism by which mutant SOD1 can induce ALS is not fully understood. There is currently no cure for ALS or treatment that significantly reduces symptoms or progression. To develop tools to under...

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Detalles Bibliográficos
Autores principales: Broering, Teresa J., Wang, Hongyan, Boatright, Naomi K., Wang, Yang, Baptista, Katherine, Shayan, Gilda, Garrity, Kerry A., Kayatekin, Can, Bosco, Daryl A., Matthews, C. Robert, Ambrosino, Donna M., Xu, Zuoshang, Babcock, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629177/
https://www.ncbi.nlm.nih.gov/pubmed/23613814
http://dx.doi.org/10.1371/journal.pone.0061210

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