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Mechanistic Explanations for Restricted Evolutionary Paths That Emerge from Gene Regulatory Networks

The extent and the nature of the constraints to evolutionary trajectories are central issues in biology. Constraints can be the result of systems dynamics causing a non-linear mapping between genotype and phenotype. How prevalent are these developmental constraints and what is their mechanistic basi...

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Detalles Bibliográficos
Autores principales: Cotterell, James, Sharpe, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629181/
https://www.ncbi.nlm.nih.gov/pubmed/23613807
http://dx.doi.org/10.1371/journal.pone.0061178