EZH2 Mutations Are Related to Low Blast Percentage in Bone Marrow and -7/del(7q) in De Novo Acute Myeloid Leukemia

The purpose of the present work was to determine the incidence and clinical implications of somatic EZH2 mutations in 714 patients with de novo acute myelogenous leukemia by sequencing the entire coding region. EZH2 mutations were identified in 13/714 (1.8%) of AML patients were found to be more com...

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Detalles Bibliográficos
Autores principales: Wang, Xiuli, Dai, Haiping, Wang, Qian, Wang, Qinrong, Xu, Yang, Wang, Ying, Sun, Aining, Ruan, Jia, Chen, Suning, Wu, Depei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629223/
https://www.ncbi.nlm.nih.gov/pubmed/23613835
http://dx.doi.org/10.1371/journal.pone.0061341

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