Small antibody fusion proteins with complementarity-determining regions and lidamycin for tumor targeting therapy

Gelatinases are overexpressed in several types of maligancies and tumor stromal cells. Lidamycin is an enediyne antitumor antibiotic, which is composed of an apoprotein (LDP) and an active chromophore (AE). It is known that the heavy-chain complementarity-determining region-3 (CDR3) domain of scFv i...

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Detalles Bibliográficos
Autores principales: ZHONG, GEN-SHEN, WU, MIN-NA, GUO, XIAO-FANG, XU, ZHI-SHAN, ZHANG, SHENG-HUA, ZHEN, YONG-SU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629231/
https://www.ncbi.nlm.nih.gov/pubmed/23599760
http://dx.doi.org/10.3892/ol.2013.1143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629231/
https://www.ncbi.nlm.nih.gov/pubmed/23599760
http://dx.doi.org/10.3892/ol.2013.1143

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