Double-stranded RNA induces molecular and inflammatory signatures that are directly relevant to COPD

Polyinosinic:polycytidylic acid (poly I:C) is a synthetic analogue of double-stranded (ds)RNA, a molecular pattern associated with viral infections, that is used to exacerbate inflammation in lung injury models. Despite its frequent use, there are no detailed studies of the responses elicited by a s...

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Detalles Bibliográficos
Autores principales: Harris, P, Sridhar, S, Peng, R, Phillips, J E, Cohn, R G, Burns, L, Woods, J, Ramanujam, M, Loubeau, M, Tyagi, G, Allard, J, Burczynski, M, Ravindran, P, Cheng, D, Bitter, H, Fine, J S, Bauer, C M T, Stevenson, C S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629368/
https://www.ncbi.nlm.nih.gov/pubmed/22990623
http://dx.doi.org/10.1038/mi.2012.86

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