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3-(4-Chloro­phen­yl)-5-(4-eth­oxy­phen­yl)-4,5-dihydro-1H-pyrazole-1-carbothio­amide ethanol monosolvate

The asymmetric unit of the title compound, C(18)H(18)ClN(3)OS·C(2)H(5)OH, comprises a pyrazoline derivative and an ethanol solvent mol­ecule. In the mol­ecule of the pyrazoline derivative, the pyrazole ring adopts an envelope conformation with the C atom bearing the eth­oxy­phenyl substituent as the...

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Detalles Bibliográficos
Autores principales: Quah, Ching Kheng, Fun, Hoong-Kun, Suwunwong, Thitipone, Boonnak, Nawong, Chantrapromma, Suchada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629506/
https://www.ncbi.nlm.nih.gov/pubmed/23634024
http://dx.doi.org/10.1107/S1600536813005369
Descripción
Sumario:The asymmetric unit of the title compound, C(18)H(18)ClN(3)OS·C(2)H(5)OH, comprises a pyrazoline derivative and an ethanol solvent mol­ecule. In the mol­ecule of the pyrazoline derivative, the pyrazole ring adopts an envelope conformation with the C atom bearing the eth­oxy­phenyl substituent as the flap. The dihedral angle between the benzene rings is 74.22 (7)°. The eth­oxy group is coplanar with the attached benzene ring [C—O—C—C(meth­yl) = 175.50 (11)° and r.m.s. deviation = 0.0459 (1) Å for the nine non-H atoms]. In the crystal, the pyrazoline mol­ecules are linked by N—H⋯O(eth­oxy) hydrogen bonds into chains along the c axis and are further linked with the solvent ethanol mol­ecules by N—H⋯O(ethanol) and O(ethanol)—H⋯S hydrogen bonds. C—H⋯π inter­actions are also present.