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(1′S,12′R,13′S,17′S)-15′,15′-Dimethyl-1,2-dihydro-11′,14′,16′,18′-tetraoxa-7′-azaspiro[indole-3,8′-pentacyclo[10.6.0.0(2,9).0(3,7).0(13,17)]octadecane]-2,10′-dione
In the title compound, C(22)H(24)N(2)O(6), the indole ring has a twist conformation and the tetrahydro-2H-pyran-2-one ring a half-chair conformation. One of the pyrrolidine rings adopts an envelope conformation on the N atom, while the other has a twist conformation; the ‘butterfly’ angle between t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629507/ https://www.ncbi.nlm.nih.gov/pubmed/23634025 http://dx.doi.org/10.1107/S1600536813005436 |
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author | Sabari, V. Ponnusamy, R. Prasanna, R. Raghunathan, R. Aravindhan, S. |
author_facet | Sabari, V. Ponnusamy, R. Prasanna, R. Raghunathan, R. Aravindhan, S. |
author_sort | Sabari, V. |
collection | PubMed |
description | In the title compound, C(22)H(24)N(2)O(6), the indole ring has a twist conformation and the tetrahydro-2H-pyran-2-one ring a half-chair conformation. One of the pyrrolidine rings adopts an envelope conformation on the N atom, while the other has a twist conformation; the ‘butterfly’ angle between their mean planes is 62.98 (11)°. The dioxolane ring adopts a twist conformation and the tetrahydrofuran ring has an envelope conformation on the C atom in the fused tetrahydro-2H-pyran-2-one ring adjacent to the O atom of the tetrahydrofuran ring. The ‘butterfly’ angle between the mean planes of these two five-membered rings is 69.14 (10)°. In the crystal, molecules are linked by N—H⋯O hydrogen bonds, forming chains along the a axis. |
format | Online Article Text |
id | pubmed-3629507 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-36295072013-04-30 (1′S,12′R,13′S,17′S)-15′,15′-Dimethyl-1,2-dihydro-11′,14′,16′,18′-tetraoxa-7′-azaspiro[indole-3,8′-pentacyclo[10.6.0.0(2,9).0(3,7).0(13,17)]octadecane]-2,10′-dione Sabari, V. Ponnusamy, R. Prasanna, R. Raghunathan, R. Aravindhan, S. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(22)H(24)N(2)O(6), the indole ring has a twist conformation and the tetrahydro-2H-pyran-2-one ring a half-chair conformation. One of the pyrrolidine rings adopts an envelope conformation on the N atom, while the other has a twist conformation; the ‘butterfly’ angle between their mean planes is 62.98 (11)°. The dioxolane ring adopts a twist conformation and the tetrahydrofuran ring has an envelope conformation on the C atom in the fused tetrahydro-2H-pyran-2-one ring adjacent to the O atom of the tetrahydrofuran ring. The ‘butterfly’ angle between the mean planes of these two five-membered rings is 69.14 (10)°. In the crystal, molecules are linked by N—H⋯O hydrogen bonds, forming chains along the a axis. International Union of Crystallography 2013-03-02 /pmc/articles/PMC3629507/ /pubmed/23634025 http://dx.doi.org/10.1107/S1600536813005436 Text en © Sabari et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Sabari, V. Ponnusamy, R. Prasanna, R. Raghunathan, R. Aravindhan, S. (1′S,12′R,13′S,17′S)-15′,15′-Dimethyl-1,2-dihydro-11′,14′,16′,18′-tetraoxa-7′-azaspiro[indole-3,8′-pentacyclo[10.6.0.0(2,9).0(3,7).0(13,17)]octadecane]-2,10′-dione |
title | (1′S,12′R,13′S,17′S)-15′,15′-Dimethyl-1,2-dihydro-11′,14′,16′,18′-tetraoxa-7′-azaspiro[indole-3,8′-pentacyclo[10.6.0.0(2,9).0(3,7).0(13,17)]octadecane]-2,10′-dione |
title_full | (1′S,12′R,13′S,17′S)-15′,15′-Dimethyl-1,2-dihydro-11′,14′,16′,18′-tetraoxa-7′-azaspiro[indole-3,8′-pentacyclo[10.6.0.0(2,9).0(3,7).0(13,17)]octadecane]-2,10′-dione |
title_fullStr | (1′S,12′R,13′S,17′S)-15′,15′-Dimethyl-1,2-dihydro-11′,14′,16′,18′-tetraoxa-7′-azaspiro[indole-3,8′-pentacyclo[10.6.0.0(2,9).0(3,7).0(13,17)]octadecane]-2,10′-dione |
title_full_unstemmed | (1′S,12′R,13′S,17′S)-15′,15′-Dimethyl-1,2-dihydro-11′,14′,16′,18′-tetraoxa-7′-azaspiro[indole-3,8′-pentacyclo[10.6.0.0(2,9).0(3,7).0(13,17)]octadecane]-2,10′-dione |
title_short | (1′S,12′R,13′S,17′S)-15′,15′-Dimethyl-1,2-dihydro-11′,14′,16′,18′-tetraoxa-7′-azaspiro[indole-3,8′-pentacyclo[10.6.0.0(2,9).0(3,7).0(13,17)]octadecane]-2,10′-dione |
title_sort | (1′s,12′r,13′s,17′s)-15′,15′-dimethyl-1,2-dihydro-11′,14′,16′,18′-tetraoxa-7′-azaspiro[indole-3,8′-pentacyclo[10.6.0.0(2,9).0(3,7).0(13,17)]octadecane]-2,10′-dione |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629507/ https://www.ncbi.nlm.nih.gov/pubmed/23634025 http://dx.doi.org/10.1107/S1600536813005436 |
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