7-Hy­droxy­methyl-2-pivaloyl­amino-1,8-naphthyridine

In the title compound, C(14)H(17)N(3)O(2), the mean plane of the 1,8-naphthyridine ring system (r.m.s deviation = 0.020 Å) forms a dihedral angle of 23.4 (1)° with the acetamide moiety (r.m.s deviation = 0.001 Å). The mol­ecular structure is stabilized by an intra­molecular O—H⋯N hydrogen bond, whic...

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Autores principales: Fun, Hoong-Kun, Quah, Ching Kheng, Aich, Krishnendu, Das, Sangita, Goswami, Shyamaprosad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629533/
https://www.ncbi.nlm.nih.gov/pubmed/23634051
http://dx.doi.org/10.1107/S1600536813005527
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author Fun, Hoong-Kun
Quah, Ching Kheng
Aich, Krishnendu
Das, Sangita
Goswami, Shyamaprosad
author_facet Fun, Hoong-Kun
Quah, Ching Kheng
Aich, Krishnendu
Das, Sangita
Goswami, Shyamaprosad
author_sort Fun, Hoong-Kun
collection PubMed
description In the title compound, C(14)H(17)N(3)O(2), the mean plane of the 1,8-naphthyridine ring system (r.m.s deviation = 0.020 Å) forms a dihedral angle of 23.4 (1)° with the acetamide moiety (r.m.s deviation = 0.001 Å). The mol­ecular structure is stabilized by an intra­molecular O—H⋯N hydrogen bond, which generates an S(5) ring motif. In the crystal, mol­ecules are linked into inversion dimers by pairs of N—H⋯O hydrogen bonds, generating 18-membered R (2) (2)(18) ring motifs.
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spelling pubmed-36295332013-04-30 7-Hy­droxy­methyl-2-pivaloyl­amino-1,8-naphthyridine Fun, Hoong-Kun Quah, Ching Kheng Aich, Krishnendu Das, Sangita Goswami, Shyamaprosad Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(14)H(17)N(3)O(2), the mean plane of the 1,8-naphthyridine ring system (r.m.s deviation = 0.020 Å) forms a dihedral angle of 23.4 (1)° with the acetamide moiety (r.m.s deviation = 0.001 Å). The mol­ecular structure is stabilized by an intra­molecular O—H⋯N hydrogen bond, which generates an S(5) ring motif. In the crystal, mol­ecules are linked into inversion dimers by pairs of N—H⋯O hydrogen bonds, generating 18-membered R (2) (2)(18) ring motifs. International Union of Crystallography 2013-03-06 /pmc/articles/PMC3629533/ /pubmed/23634051 http://dx.doi.org/10.1107/S1600536813005527 Text en © Fun et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Fun, Hoong-Kun
Quah, Ching Kheng
Aich, Krishnendu
Das, Sangita
Goswami, Shyamaprosad
7-Hy­droxy­methyl-2-pivaloyl­amino-1,8-naphthyridine
title 7-Hy­droxy­methyl-2-pivaloyl­amino-1,8-naphthyridine
title_full 7-Hy­droxy­methyl-2-pivaloyl­amino-1,8-naphthyridine
title_fullStr 7-Hy­droxy­methyl-2-pivaloyl­amino-1,8-naphthyridine
title_full_unstemmed 7-Hy­droxy­methyl-2-pivaloyl­amino-1,8-naphthyridine
title_short 7-Hy­droxy­methyl-2-pivaloyl­amino-1,8-naphthyridine
title_sort 7-hy­droxy­methyl-2-pivaloyl­amino-1,8-naphthyridine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629533/
https://www.ncbi.nlm.nih.gov/pubmed/23634051
http://dx.doi.org/10.1107/S1600536813005527
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