Ethyl 2,6-bis­(4-chloro­phen­yl)-4-(4-fluoro­anilino)-1-(4-fluoro­phen­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate

In the title compound, C(32)H(26)Cl(2)F(2)N(2)O(2), the tetra­hydro­pyridine ring adopts a distorted boat conformation. The chlorophenyl rings are inclined to one another by 55.2 (1)°, while for the fluorophenyl rings the dihedral angle is 80.7 (1)°. The amino group and carbonyl O atom are involved...

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Autores principales: Anthal, Sumati, Brahmachari, Goutam, Das, Suvankar, Kant, Rajni, Gupta, Vivek K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629536/
https://www.ncbi.nlm.nih.gov/pubmed/23634054
http://dx.doi.org/10.1107/S1600536813006090
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author Anthal, Sumati
Brahmachari, Goutam
Das, Suvankar
Kant, Rajni
Gupta, Vivek K.
author_facet Anthal, Sumati
Brahmachari, Goutam
Das, Suvankar
Kant, Rajni
Gupta, Vivek K.
author_sort Anthal, Sumati
collection PubMed
description In the title compound, C(32)H(26)Cl(2)F(2)N(2)O(2), the tetra­hydro­pyridine ring adopts a distorted boat conformation. The chlorophenyl rings are inclined to one another by 55.2 (1)°, while for the fluorophenyl rings the dihedral angle is 80.7 (1)°. The amino group and carbonyl O atom are involved in an intra­molecular N—H⋯O hydrogen bond. In the crystal, weak C—H⋯O, C—H⋯F and C—H⋯Cl inter­actions link the mol­ecules into a three-dimensional network.
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spelling pubmed-36295362013-04-30 Ethyl 2,6-bis­(4-chloro­phen­yl)-4-(4-fluoro­anilino)-1-(4-fluoro­phen­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate Anthal, Sumati Brahmachari, Goutam Das, Suvankar Kant, Rajni Gupta, Vivek K. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(32)H(26)Cl(2)F(2)N(2)O(2), the tetra­hydro­pyridine ring adopts a distorted boat conformation. The chlorophenyl rings are inclined to one another by 55.2 (1)°, while for the fluorophenyl rings the dihedral angle is 80.7 (1)°. The amino group and carbonyl O atom are involved in an intra­molecular N—H⋯O hydrogen bond. In the crystal, weak C—H⋯O, C—H⋯F and C—H⋯Cl inter­actions link the mol­ecules into a three-dimensional network. International Union of Crystallography 2013-03-09 /pmc/articles/PMC3629536/ /pubmed/23634054 http://dx.doi.org/10.1107/S1600536813006090 Text en © Anthal et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Anthal, Sumati
Brahmachari, Goutam
Das, Suvankar
Kant, Rajni
Gupta, Vivek K.
Ethyl 2,6-bis­(4-chloro­phen­yl)-4-(4-fluoro­anilino)-1-(4-fluoro­phen­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title Ethyl 2,6-bis­(4-chloro­phen­yl)-4-(4-fluoro­anilino)-1-(4-fluoro­phen­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_full Ethyl 2,6-bis­(4-chloro­phen­yl)-4-(4-fluoro­anilino)-1-(4-fluoro­phen­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_fullStr Ethyl 2,6-bis­(4-chloro­phen­yl)-4-(4-fluoro­anilino)-1-(4-fluoro­phen­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_full_unstemmed Ethyl 2,6-bis­(4-chloro­phen­yl)-4-(4-fluoro­anilino)-1-(4-fluoro­phen­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_short Ethyl 2,6-bis­(4-chloro­phen­yl)-4-(4-fluoro­anilino)-1-(4-fluoro­phen­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_sort ethyl 2,6-bis­(4-chloro­phen­yl)-4-(4-fluoro­anilino)-1-(4-fluoro­phen­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629536/
https://www.ncbi.nlm.nih.gov/pubmed/23634054
http://dx.doi.org/10.1107/S1600536813006090
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AT dassuvankar ethyl26bis4chlorophenyl44fluoroanilino14fluorophenyl1256tetrahydropyridine3carboxylate
AT kantrajni ethyl26bis4chlorophenyl44fluoroanilino14fluorophenyl1256tetrahydropyridine3carboxylate
AT guptavivekk ethyl26bis4chlorophenyl44fluoroanilino14fluorophenyl1256tetrahydropyridine3carboxylate

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