Cargando…

1-(4-Bromo-3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethan-1-one: a precursor for phase-I metabolite of AHTN

The title compound, C(18)H(25)BrO, crystallized as a racemate with four independent molecules in the asymmetric unit. In the crystal, three of these four molecules are linked via C—Br⋯Br—C halogen bonds [Br⋯Br = 3.662 (2) and 3.652 (2) Å], forming dimers.

Detalles Bibliográficos
Autores principales:	Kuhlich, Paul, Emmerling, Franziska, Kraus, Werner, Nehls, Irene, Piechotta, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2013
Materias:	Organic Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629597/ https://www.ncbi.nlm.nih.gov/pubmed/23634084 http://dx.doi.org/10.1107/S1600536813006934

Ejemplares similares

Methyl 3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydronaphthalene-2-carboxylate (AHTN–COOMe)
por: Kuhlich, Paul, et al.
Publicado: (2011)

(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)methanol: a possible metabolite of the synthetic musk fragrance AHTN
por: Faust, Rüdiger, et al.
Publicado: (2011)

3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydro-2-naphthoic acid (AHTN–COOH)
por: Kuhlich, Paul, et al.
Publicado: (2010)

5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid
por: Zou, Pei, et al.
Publicado: (2009)

(Naphthalen-1-yl){2-[(5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]phenyl}methanone
por: Kanchanadevi, J., et al.
Publicado: (2013)

8,8-Diethyl-1,4,5,8-tetrahydronaphthalene-1,4,5-trione
por: Vega, Andrés, et al.
Publicado: (2009)

Crystal structure and Hirshfeld surface analysis of (E)-N-[(2-ethoxynaphthalen-1-yl)methylidene]-5,6,7,8-tetrahydronaphthalen-1-amine
por: Kansiz, Sevgi, et al.
Publicado: (2018)

Crystal structure and Hirshfeld surface analysis of (E)-N-[(2-ethoxynaphthalen-1-yl)methylidene]-5,6,7,8-tetrahydronaphthalen-1-amine. Corrigendum
por: Kansiz, Sevgi, et al.
Publicado: (2018)

5,6,7,8-Tetrahydroquinolin-8-one
por: Lipińska, Teodozja M., et al.
Publicado: (2011)

5,6,7,8-Tetrahydroquinoline 1-oxide hemihydrate
por: Karczmarzyk, Zbigniew, et al.
Publicado: (2010)

Novel Synthesis of 8-Deaza-5,6,7,8-tetrahydroaminopterin Analogues via an Aziridine Intermediate
por: Zhou, Shouxin, et al.
Publicado: (2012)

(±)-(4aR,5R,8S,8aR)-8-(tert-Butyldimethylsilyloxy)-2,5,8a-trimethyl-4a,5,8,8a-tetrahydronaphthalene-1,4-dione
por: Delling, Felix N., et al.
Publicado: (2013)

Biological Properties of New Chiral 2-Methyl-5,6,7,8-tetrahydroquinolin-8-amine-based Compounds
por: Facchetti, Giorgio, et al.
Publicado: (2020)

Synthesis and X-ray Crystal Structure of Meso-5,5,7,12,12,14-hexamethyl-1,4,8,11-tetraazacyclotetradecane-1,8-di-(1-methyl-naphthalene)
por: Haines, Robert I., et al.
Publicado: (2003)

2,4-Bis(arylethynyl)-9-chloro-5,6,7,8-tetrahydroacridines: synthesis and photophysical properties
por: Tka, Najeh, et al.
Publicado: (2021)

3,3,6,6,9,9-Hexamethyl-2,3,4,5,6,7,8,9-octahydro-1H-xanthene-1,8-dione
por: Xie, Xiaofen, et al.
Publicado: (2009)

2-Amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
por: Wang, Xiaoli
Publicado: (2011)

Crystal structure of 2-amino-5,6,7,8-tetrahydro-7,7-dimethyl-4-(naphthalen-2-yl)-5-oxo-4H-chromene-3-carbonitrile
por: Hebishy, Ali M. S., et al.
Publicado: (2022)

4-(4-Methoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydrochromene-2,5-dione
por: Shi, Hao
Publicado: (2009)

8-(4-Chlorobenzylidene)-4-(4-chlorophenyl)-2-phenyl-5,6,7,8-tetrahydroquinoline
por: Jian, Fangfang, et al.
Publicado: (2010)

1,3-Dimethyl-5,6,7,8-tetrahydro-4H-cyclohepta[c]thiophene-4,8-dione
por: Yu, Lijuan, et al.
Publicado: (2010)

Synthesis and investigation on optical and electrochemical properties of 2,4-diaryl-9-chloro-5,6,7,8-tetrahydroacridines
por: Tka, Najeh, et al.
Publicado: (2021)

Synthesis of Novel Derivatives of 5,6,7,8-Tetrahydroquinazolines Using α-Aminoamidines and In Silico Screening of Their Biological Activity
por: Snizhko, Arsenii D., et al.
Publicado: (2022)

5,6,7,8-Tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-9(4H)-one
por: Ettahiri, Walid, et al.
Publicado: (2023)

3-(5,6,7,8-Tetrahydro-2-naphthyl)isobenzofuran-1(3H)-one
por: Kitamura, Chitoshi, et al.
Publicado: (2008)

Synthesis and antibacterial activity of novel 5,6,7,8-tetrahydroimidazo[1,2-a]pyrimidine-2-carbohydrazide derivatives
por: Kethireddy, Shashikala, et al.
Publicado: (2015)

Design, Synthesis, and Biological Evaluation of 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines as Microtubule Targeting Agents
por: Islam, Farhana, et al.
Publicado: (2022)

3,3′-(5,5,7,12,12,14-Hexamethyl-1,4,8,11-tetraazacyclotetradecane-1,8-diyl)dipropanonitrile methanol disolvate
por: Hao, Cheng-Jun, et al.
Publicado: (2010)

2-Amino-4-(4-chlorophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
por: Mohamed, Shaaban K., et al.
Publicado: (2012)

2-Amino-4-(4-methylphenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
por: Mohamed, Shaaban K., et al.
Publicado: (2012)

Ethyl 4-(4-chlorophenyl)-2-methyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-carboxylate
por: Wang, Ke, et al.
Publicado: (2013)

2-[(2-Hydroxynaphthalen-1-yl)methylideneamino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile
por: Asiri, Abdullah M., et al.
Publicado: (2013)

Hexamethyl 13,14-dioxapentacyclo[8.2.1.1(4,7).0(2,9).0(3,8)]tetradeca-5,11-diene-1,4,5,6,11,12-hexacarboxylate
por: Lough, Alan J., et al.
Publicado: (2012)

7-Methyl-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidin-4-amine
por: Ziaulla, Mohamed, et al.
Publicado: (2011)

2-Phenyl-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]benzothiazole
por: Bunev, Alexander S., et al.
Publicado: (2014)

Chiral 8-Amino-5,6,7,8-tetrahydroquinoline Derivatives in Metal Catalysts for the Asymmetric Transfer Hydrogenation of 1-Aryl Substituted-3,4-dihydroisoquinolines as Alkaloids Precursors
por: Facchetti, Giorgio, et al.
Publicado: (2023)

Protective effects of (6R)-5,6,7,8-tetrahydro-l-biopterin on local ischemia/reperfusion-induced suppression of reactive hyperemia in rat gingiva
por: Tanaka, Yusaku, et al.
Publicado: (2016)

2-Amino-4-[4-(dimethylamino)phenyl]-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
por: Qiao, Yan, et al.
Publicado: (2011)

2-Amino-4-(4-methoxyphenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
por: Kong, Lingqian, et al.
Publicado: (2011)

4-(4-Bromophenyl)-2-methylamino-3-nitro-5,6,7,8-tetrahydro-4H-chromen-5-one
por: Narayanan, P., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_n7htnbnr65n54d4su70hkhsla9