N-(2-Meth­oxy­benz­yl)-9-(oxolan-2-yl)-9H-purin-6-amine

The title compound, C(17)H(19)N(5)O(2), features an almost planar purine skeleton (r.m.s. deviation = 0.009 Å) substituted by a tetra­hydro­furan ring, which adopts an envelope conformation. The purine and benzene rings subtend a dihedral angle of 66.70 (3)°. In the crystal, pairs of N—H⋯N hydrogen...

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Autores principales: Trávníček, Zdeněk, Popa, Igor, Dvořák, Zdeněk, Štarha, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629632/
https://www.ncbi.nlm.nih.gov/pubmed/23634119
http://dx.doi.org/10.1107/S1600536813007721
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author Trávníček, Zdeněk
Popa, Igor
Dvořák, Zdeněk
Štarha, Pavel
author_facet Trávníček, Zdeněk
Popa, Igor
Dvořák, Zdeněk
Štarha, Pavel
author_sort Trávníček, Zdeněk
collection PubMed
description The title compound, C(17)H(19)N(5)O(2), features an almost planar purine skeleton (r.m.s. deviation = 0.009 Å) substituted by a tetra­hydro­furan ring, which adopts an envelope conformation. The purine and benzene rings subtend a dihedral angle of 66.70 (3)°. In the crystal, pairs of N—H⋯N hydrogen bonds connect adjacent mol­ecules into inversion dimers. C—H⋯N, C—H⋯O, C—H⋯π and π–π inter­actions [pyrimidine ring centroid–centroid distance = 3.3909 (1) Å] connect the dimers into a three-dimensional architecture.
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spelling pubmed-36296322013-04-30 N-(2-Meth­oxy­benz­yl)-9-(oxolan-2-yl)-9H-purin-6-amine Trávníček, Zdeněk Popa, Igor Dvořák, Zdeněk Štarha, Pavel Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(17)H(19)N(5)O(2), features an almost planar purine skeleton (r.m.s. deviation = 0.009 Å) substituted by a tetra­hydro­furan ring, which adopts an envelope conformation. The purine and benzene rings subtend a dihedral angle of 66.70 (3)°. In the crystal, pairs of N—H⋯N hydrogen bonds connect adjacent mol­ecules into inversion dimers. C—H⋯N, C—H⋯O, C—H⋯π and π–π inter­actions [pyrimidine ring centroid–centroid distance = 3.3909 (1) Å] connect the dimers into a three-dimensional architecture. International Union of Crystallography 2013-03-23 /pmc/articles/PMC3629632/ /pubmed/23634119 http://dx.doi.org/10.1107/S1600536813007721 Text en © Trávníček et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Trávníček, Zdeněk
Popa, Igor
Dvořák, Zdeněk
Štarha, Pavel
N-(2-Meth­oxy­benz­yl)-9-(oxolan-2-yl)-9H-purin-6-amine
title N-(2-Meth­oxy­benz­yl)-9-(oxolan-2-yl)-9H-purin-6-amine
title_full N-(2-Meth­oxy­benz­yl)-9-(oxolan-2-yl)-9H-purin-6-amine
title_fullStr N-(2-Meth­oxy­benz­yl)-9-(oxolan-2-yl)-9H-purin-6-amine
title_full_unstemmed N-(2-Meth­oxy­benz­yl)-9-(oxolan-2-yl)-9H-purin-6-amine
title_short N-(2-Meth­oxy­benz­yl)-9-(oxolan-2-yl)-9H-purin-6-amine
title_sort n-(2-meth­oxy­benz­yl)-9-(oxolan-2-yl)-9h-purin-6-amine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629632/
https://www.ncbi.nlm.nih.gov/pubmed/23634119
http://dx.doi.org/10.1107/S1600536813007721
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