C3G forms complexes with Bcr-Abl and p38α MAPK at the focal adhesions in chronic myeloid leukemia cells: implication in the regulation of leukemic cell adhesion

BACKGROUND: Previous studies by our group and others have shown that C3G interacts with Bcr-Abl through its SH3-b domain. RESULTS: In this work we show that C3G and Bcr-Abl form complexes with the focal adhesion (FA) proteins CrkL, p130Cas, Cbl and Abi1 through SH3/SH3-b interactions. The associatio...

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Detalles Bibliográficos
Autores principales: Maia, Vera, Ortiz-Rivero, Sara, Sanz, María, Gutierrez-Berzal, Javier, Álvarez-Fernández, Indira, Gutierrez-Herrero, Sara, de Pereda, Jose María, Porras, Almudena, Guerrero, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629710/
https://www.ncbi.nlm.nih.gov/pubmed/23343344
http://dx.doi.org/10.1186/1478-811X-11-9

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