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Non-optimal codon usage affects expression, structure and function of FRQ clock protein
Codon usage bias has been observed in almost all genomes and is thought to result from selection for efficient and accurate translation of highly expressed genes(1–3). Codon usage is also implicated in the control of transcription, splicing and RNA structure(4–6). Many genes exhibit little codon usa...
Autores principales: | Zhou, Mian, Guo, Jinhu, Cha, Joonseok, Chae, Michael, Chen, She, Barral, Jose M., Sachs, Matthew S., Liu, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629845/ https://www.ncbi.nlm.nih.gov/pubmed/23417067 http://dx.doi.org/10.1038/nature11833 |
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