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Risk factors for high-altitude headache upon acute high-altitude exposure at 3700 m in young Chinese men: a cohort study

BACKGROUND: This prospective and observational study aimed to identify demographic, physiological and psychological risk factors associated with high-altitude headache (HAH) upon acute high-altitude exposure. METHODS: Eight hundred fifty subjects ascended by plane to 3700 m above Chengdu (500 m) ove...

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Autores principales: Bian, Shi-Zhu, Zhang, Ji-Hang, Gao, Xu-Bin, Li, Ming, Yu, Jie, Liu, Xi, Dong, Jun-Qing, Chen, Guo-Zhu, Huang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630053/
https://www.ncbi.nlm.nih.gov/pubmed/23578252
http://dx.doi.org/10.1186/1129-2377-14-35
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author Bian, Shi-Zhu
Zhang, Ji-Hang
Gao, Xu-Bin
Li, Ming
Yu, Jie
Liu, Xi
Dong, Jun-Qing
Chen, Guo-Zhu
Huang, Lan
author_facet Bian, Shi-Zhu
Zhang, Ji-Hang
Gao, Xu-Bin
Li, Ming
Yu, Jie
Liu, Xi
Dong, Jun-Qing
Chen, Guo-Zhu
Huang, Lan
author_sort Bian, Shi-Zhu
collection PubMed
description BACKGROUND: This prospective and observational study aimed to identify demographic, physiological and psychological risk factors associated with high-altitude headache (HAH) upon acute high-altitude exposure. METHODS: Eight hundred fifty subjects ascended by plane to 3700 m above Chengdu (500 m) over a period of two hours. Structured Case Report Form (CRF) questionnaires were used to record demographic information, physiological examinations, psychological scale, and symptoms including headache and insomnia a week before ascending and within 24 hours after arrival at 3700 m. Binary logistic regression models were used to analyze the risk factors for HAH. RESULTS: The incidence of HAH was 73.3%. Age (p =0.011), physical labor intensity (PLI) (p =0.044), primary headache history (p <0.001), insomnia (p <0.001), arterial oxygen saturation (SaO(2)) (p =0.001), heart rate (HR) (p =0.002), the Self-Rating Anxiety Scale (SAS) (p <0.001), and the Epworth Sleepiness Scale (ESS) (p <0.001) were significantly different between HAH and non-HAH groups. Logistic regression models identified primary headache history, insomnia, low SaO(2), high HR and SAS as independent risk factors for HAH. CONCLUSIONS: Insomnia, primary headache history, low SaO(2), high HR, and high SAS score are the risk factors for HAH. Our findings will provide novel avenues for the study, prevention and treatment of HAH.
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spelling pubmed-36300532013-04-22 Risk factors for high-altitude headache upon acute high-altitude exposure at 3700 m in young Chinese men: a cohort study Bian, Shi-Zhu Zhang, Ji-Hang Gao, Xu-Bin Li, Ming Yu, Jie Liu, Xi Dong, Jun-Qing Chen, Guo-Zhu Huang, Lan J Headache Pain Research Article BACKGROUND: This prospective and observational study aimed to identify demographic, physiological and psychological risk factors associated with high-altitude headache (HAH) upon acute high-altitude exposure. METHODS: Eight hundred fifty subjects ascended by plane to 3700 m above Chengdu (500 m) over a period of two hours. Structured Case Report Form (CRF) questionnaires were used to record demographic information, physiological examinations, psychological scale, and symptoms including headache and insomnia a week before ascending and within 24 hours after arrival at 3700 m. Binary logistic regression models were used to analyze the risk factors for HAH. RESULTS: The incidence of HAH was 73.3%. Age (p =0.011), physical labor intensity (PLI) (p =0.044), primary headache history (p <0.001), insomnia (p <0.001), arterial oxygen saturation (SaO(2)) (p =0.001), heart rate (HR) (p =0.002), the Self-Rating Anxiety Scale (SAS) (p <0.001), and the Epworth Sleepiness Scale (ESS) (p <0.001) were significantly different between HAH and non-HAH groups. Logistic regression models identified primary headache history, insomnia, low SaO(2), high HR and SAS as independent risk factors for HAH. CONCLUSIONS: Insomnia, primary headache history, low SaO(2), high HR, and high SAS score are the risk factors for HAH. Our findings will provide novel avenues for the study, prevention and treatment of HAH. Springer 2013 2013-04-11 /pmc/articles/PMC3630053/ /pubmed/23578252 http://dx.doi.org/10.1186/1129-2377-14-35 Text en Copyright ©2013 Bian et al.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Bian, Shi-Zhu
Zhang, Ji-Hang
Gao, Xu-Bin
Li, Ming
Yu, Jie
Liu, Xi
Dong, Jun-Qing
Chen, Guo-Zhu
Huang, Lan
Risk factors for high-altitude headache upon acute high-altitude exposure at 3700 m in young Chinese men: a cohort study
title Risk factors for high-altitude headache upon acute high-altitude exposure at 3700 m in young Chinese men: a cohort study
title_full Risk factors for high-altitude headache upon acute high-altitude exposure at 3700 m in young Chinese men: a cohort study
title_fullStr Risk factors for high-altitude headache upon acute high-altitude exposure at 3700 m in young Chinese men: a cohort study
title_full_unstemmed Risk factors for high-altitude headache upon acute high-altitude exposure at 3700 m in young Chinese men: a cohort study
title_short Risk factors for high-altitude headache upon acute high-altitude exposure at 3700 m in young Chinese men: a cohort study
title_sort risk factors for high-altitude headache upon acute high-altitude exposure at 3700 m in young chinese men: a cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630053/
https://www.ncbi.nlm.nih.gov/pubmed/23578252
http://dx.doi.org/10.1186/1129-2377-14-35
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