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Bovine HEXIM1 inhibits bovine immunodeficiency virus replication through regulating BTat-mediated transactivation
The bovine immunodeficiency virus (BIV) transactivator (BTat) recruits the bovine cyclin T1 (B-cyclin T1) to the LTR to facilitate the transcription of BIV. Here, we demonstrate that bovine hexamethylene bisacetamide (HMBA)-induced protein 1 (BHEXIM1) inhibits BTat-mediated BIV LTR transcription. Th...
Autores principales: | Guo, Hong-yan, Ma, Yong-gang, Gai, Yuan-ming, Liang, Zhi-bin, Ma, Jing, Su, Yang, Zhang, Qi-cheng, Chen, Qi-min, Tan, Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630055/ https://www.ncbi.nlm.nih.gov/pubmed/23537346 http://dx.doi.org/10.1186/1297-9716-44-21 |
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