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Viperin Is Induced following Dengue Virus Type-2 (DENV-2) Infection and Has Anti-viral Actions Requiring the C-terminal End of Viperin
The host protein viperin is an interferon stimulated gene (ISG) that is up-regulated during a number of viral infections. In this study we have shown that dengue virus type-2 (DENV-2) infection significantly induced viperin, co-incident with production of viral RNA and via a mechanism requiring reti...
Autores principales: | Helbig, Karla J., Carr, Jillian M., Calvert, Julie K., Wati, Satiya, Clarke, Jennifer N., Eyre, Nicholas S., Narayana, Sumudu K., Fiches, Guillaume N., McCartney, Erin M., Beard, Michael R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630087/ https://www.ncbi.nlm.nih.gov/pubmed/23638199 http://dx.doi.org/10.1371/journal.pntd.0002178 |
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