The Histone Demethylase Jarid1b Ensures Faithful Mouse Development by Protecting Developmental Genes from Aberrant H3K4me3

Embryonic development is tightly regulated by transcription factors and chromatin-associated proteins. H3K4me3 is associated with active transcription and H3K27me3 with gene repression, while the combination of both keeps genes required for development in a plastic state. Here we show that deletion...

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Detalles Bibliográficos
Autores principales: Albert, Mareike, Schmitz, Sandra U., Kooistra, Susanne M., Malatesta, Martina, Morales Torres, Cristina, Rekling, Jens C., Johansen, Jens V., Abarrategui, Iratxe, Helin, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630093/
https://www.ncbi.nlm.nih.gov/pubmed/23637629
http://dx.doi.org/10.1371/journal.pgen.1003461

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