Cytotoxic Chromosomal Targeting by CRISPR/Cas Systems Can Reshape Bacterial Genomes and Expel or Remodel Pathogenicity Islands

In prokaryotes, clustered regularly interspaced short palindromic repeats (CRISPRs) and their associated (Cas) proteins constitute a defence system against bacteriophages and plasmids. CRISPR/Cas systems acquire short spacer sequences from foreign genetic elements and incorporate these into their CR...

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Detalles Bibliográficos
Autores principales: Vercoe, Reuben B., Chang, James T., Dy, Ron L., Taylor, Corinda, Gristwood, Tamzin, Clulow, James S., Richter, Corinna, Przybilski, Rita, Pitman, Andrew R., Fineran, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630108/
https://www.ncbi.nlm.nih.gov/pubmed/23637624
http://dx.doi.org/10.1371/journal.pgen.1003454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630108/
https://www.ncbi.nlm.nih.gov/pubmed/23637624
http://dx.doi.org/10.1371/journal.pgen.1003454

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