Protease-Activated Receptor (PAR)2, but Not PAR1, Is Involved in Collateral Formation and Anti-Inflammatory Monocyte Polarization in a Mouse Hind Limb Ischemia Model

AIMS: In collateral development (i.e. arteriogenesis), mononuclear cells are important and exist as a heterogeneous population consisting of pro-inflammatory and anti-inflammatory/repair-associated cells. Protease-activated receptor (PAR)1 and PAR2 are G-protein-coupled receptors that are both expre...

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Detalles Bibliográficos
Autores principales: van den Hengel, Lisa G., Hellingman, Alwine A., Nossent, Anne Yael, van Oeveren-Rietdijk, Annemarie M., de Vries, Margreet R., Spek, C. Arnold, van Zonneveld, Anton Jan, Reitsma, Pieter H., Hamming, Jaap F., de Boer, Hetty C., Versteeg, Henri H., Quax, Paul H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630144/
https://www.ncbi.nlm.nih.gov/pubmed/23637930
http://dx.doi.org/10.1371/journal.pone.0061923

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