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Microbes Bind Complement Inhibitor Factor H via a Common Site

To cause infections microbes need to evade host defense systems, one of these being the evolutionarily old and important arm of innate immunity, the alternative pathway of complement. It can attack all kinds of targets and is tightly controlled in plasma and on host cells by plasma complement regula...

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Detalles Bibliográficos
Autores principales: Meri, T., Amdahl, H., Lehtinen, M. J., Hyvärinen, S., McDowell, J. V., Bhattacharjee, A., Meri, S., Marconi, R., Goldman, A., Jokiranta, T. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630169/
https://www.ncbi.nlm.nih.gov/pubmed/23637600
http://dx.doi.org/10.1371/journal.ppat.1003308