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Defining the Conformational Features of Anchorless, Poorly Neuroinvasive Prions

Infectious prions cause diverse clinical signs and form an extraordinary range of structures, from amorphous aggregates to fibrils. How the conformation of a prion dictates the disease phenotype remains unclear. Mice expressing GPI-anchorless or GPI-anchored prion protein exposed to the same infecti...

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Detalles Bibliográficos
Autores principales:	Bett, Cyrus, Kurt, Tim D., Lucero, Melanie, Trejo, Margarita, Rozemuller, Annemieke J., Kong, Qingzhong, Nilsson, K. Peter R., Masliah, Eliezer, Oldstone, Michael B., Sigurdson, Christina J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630170/ https://www.ncbi.nlm.nih.gov/pubmed/23637596 http://dx.doi.org/10.1371/journal.ppat.1003280

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