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Microgravity Induces Pelvic Bone Loss through Osteoclastic Activity, Osteocytic Osteolysis, and Osteoblastic Cell Cycle Inhibition by CDKN1a/p21
Bone is a dynamically remodeled tissue that requires gravity-mediated mechanical stimulation for maintenance of mineral content and structure. Homeostasis in bone occurs through a balance in the activities and signaling of osteoclasts, osteoblasts, and osteocytes, as well as proliferation and differ...
Autores principales: | Blaber, Elizabeth A., Dvorochkin, Natalya, Lee, Chialing, Alwood, Joshua S., Yousuf, Rukhsana, Pianetta, Piero, Globus, Ruth K., Burns, Brendan P., Almeida, Eduardo A. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630201/ https://www.ncbi.nlm.nih.gov/pubmed/23637819 http://dx.doi.org/10.1371/journal.pone.0061372 |
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