Cargando…
Factor H Binds to the Hypervariable Region of Many Streptococcus pyogenes M Proteins but Does Not Promote Phagocytosis Resistance or Acute Virulence
Many pathogens express a surface protein that binds the human complement regulator factor H (FH), as first described for Streptococcus pyogenes and the antiphagocytic M6 protein. It is commonly assumed that FH recruited to an M protein enhances virulence by protecting the bacteria against complement...
Autores principales: | Gustafsson, Mattias C. U., Lannergård, Jonas, Nilsson, O. Rickard, Kristensen, Bodil M., Olsen, John E., Harris, Claire L., Ufret-Vincenty, Rafael L., Stålhammar-Carlemalm, Margaretha, Lindahl, Gunnar |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630203/ https://www.ncbi.nlm.nih.gov/pubmed/23637608 http://dx.doi.org/10.1371/journal.ppat.1003323 |
Ejemplares similares
-
Sequence variability is correlated with weak immunogenicity in Streptococcus pyogenes M protein
por: Lannergård, Jonas, et al.
Publicado: (2015) -
Functional Dissection of Streptococcus pyogenes M5 Protein: the Hypervariable Region is Essential for Virulence
por: Waldemarsson, Johan, et al.
Publicado: (2009) -
Evasion of Phagocytosis through Cooperation between Two Ligand-binding Regions in Streptococcus pyogenes M Protein
por: Carlsson, Fredric, et al.
Publicado: (2003) -
Human CEACAM1 is targeted by a Streptococcus pyogenes adhesin implicated in puerperal sepsis pathogenesis
por: Catton, Erin A., et al.
Publicado: (2023) -
Author Correction: Human CEACAM1 is targeted by a Streptococcus pyogenes adhesin implicated in puerperal sepsis pathogenesis
por: Catton, Erin A., et al.
Publicado: (2023)