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Crystal Structures of E. coli Native MenH and Two Active Site Mutants
Recent revision of the biosynthetic pathway for menaquinone has led to the discovery of a previously unrecognized enzyme 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, also known as MenH. This enzyme has an α/β hydrolase fold with a catalytic triad comprising Ser86, His232, and Asp2...
Autores principales: | Johnston, Jodie M., Jiang, Ming, Guo, Zhihong, Baker, Edward N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630204/ https://www.ncbi.nlm.nih.gov/pubmed/23637813 http://dx.doi.org/10.1371/journal.pone.0061325 |
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