Gastrointestinal Stromal Tumors, Somatic Mutations and Candidate Genetic Risk Variants

Gastrointestinal stromal tumors (GISTs) are rare but treatable soft tissue sarcomas. Nearly all GISTs have somatic mutations in either the KIT or PDGFRA gene, but there are no known inherited genetic risk factors. We assessed the relationship between KIT/PDGFRA mutations and select deletions or sing...

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Detalles Bibliográficos
Autores principales: O'Brien, Katie M., Orlow, Irene, Antonescu, Cristina R., Ballman, Karla, McCall, Linda, DeMatteo, Ronald, Engel, Lawrence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630216/
https://www.ncbi.nlm.nih.gov/pubmed/23637977
http://dx.doi.org/10.1371/journal.pone.0062119

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