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Pyrroloquinoline Quinine Inhibits RANKL-Mediated Expression of NFATc1 in Part via Suppression of c-Fos in Mouse Bone Marrow Cells and Inhibits Wear Particle-Induced Osteolysis in Mice

The effects of pyrroloquinoline quinine (PQQ) on RANKL-induced osteoclast differentiation and on wear particle-induced osteolysis were examined in this study. PQQ inhibited RANKL-mediated osteoclast differentiation in bone marrow macrophages (BMMs) in a dose-dependent manner without any evidence of...

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Detalles Bibliográficos
Autores principales:	Kong, Lingbo, Yang, Chongfei, Yu, Lifeng, Smith, Wanli, Zhu, Shu, Zhu, Jinyu, Zhu, Qingsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630230/ https://www.ncbi.nlm.nih.gov/pubmed/23613773 http://dx.doi.org/10.1371/journal.pone.0061013

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