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Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover
The error-free DNA damage tolerance (DDT) pathway is crucial for replication completion and genome integrity. Mechanistically, this process is driven by a switch of templates accompanied by sister chromatid junction (SCJ) formation. Here, we asked if DDT intermediate processing is temporarily regula...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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European Molecular Biology Organization
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630363/ https://www.ncbi.nlm.nih.gov/pubmed/23531881 http://dx.doi.org/10.1038/emboj.2013.67 |