Protection of Cells against Oxidative Stress by Nanomolar Levels of Hydroxyflavones Indicates a New Type of Intracellular Antioxidant Mechanism

Natural polyphenol compounds are often good antioxidants, but they also cause damage to cells through more or less specific interactions with proteins. To distinguish antioxidant activity from cytotoxic effects we have tested four structurally related hydroxyflavones (baicalein, mosloflavone, neglet...

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Detalles Bibliográficos
Autores principales: Lombardo, Emanuele, Sabellico, Cristian, Hájek, Jan, Staňková, Veronika, Filipský, Tomáš, Balducci, Valentina, De Vito, Paolo, Leone, Stefano, Bavavea, Eugenia I., Silvestri, Ilaria Proietti, Righi, Giuliana, Luly, Paolo, Saso, Luciano, Bovicelli, Paolo, Pedersen, Jens Z., Incerpi, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630532/
https://www.ncbi.nlm.nih.gov/pubmed/23637768
http://dx.doi.org/10.1371/journal.pone.0060796

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