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Impact of Diffusion Barriers to Small Cytotoxic Molecules on the Efficacy of Immunotherapy in Breast Cancer

Molecular-focused cancer therapies, e.g., molecularly targeted therapy and immunotherapy, so far demonstrate only limited efficacy in cancer patients. We hypothesize that underestimating the role of biophysical factors that impact the delivery of drugs or cytotoxic cells to the target sites (for ass...

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Detalles Bibliográficos
Autores principales:	Das, Hiranmoy, Wang, Zhihui, Niazi, M. Khalid Khan, Aggarwal, Reeva, Lu, Jingwei, Kanji, Suman, Das, Manjusri, Joseph, Matthew, Gurcan, Metin, Cristini, Vittorio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631240/ https://www.ncbi.nlm.nih.gov/pubmed/23620747 http://dx.doi.org/10.1371/journal.pone.0061398

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