Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau

While a number of genome-wide association studies have identified microtubule-associated protein tau as a strong risk factor for Parkinson’s disease (PD), little is known about the mechanism through which human tau can predispose an individual to this disease. Here, we demonstrate that expression of...

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Detalles Bibliográficos
Autores principales: Wu, Ting-Han, Lu, Yu-Ning, Chuang, Chia-Lung, Wu, Chia-Lin, Chiang, Ann-Shyn, Krantz, David E., Chang, Hui-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631315/
https://www.ncbi.nlm.nih.gov/pubmed/23494099
http://dx.doi.org/10.1007/s00401-013-1105-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631315/
https://www.ncbi.nlm.nih.gov/pubmed/23494099
http://dx.doi.org/10.1007/s00401-013-1105-x

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