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Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau
While a number of genome-wide association studies have identified microtubule-associated protein tau as a strong risk factor for Parkinson’s disease (PD), little is known about the mechanism through which human tau can predispose an individual to this disease. Here, we demonstrate that expression of...
Autores principales: | Wu, Ting-Han, Lu, Yu-Ning, Chuang, Chia-Lung, Wu, Chia-Lin, Chiang, Ann-Shyn, Krantz, David E., Chang, Hui-Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631315/ https://www.ncbi.nlm.nih.gov/pubmed/23494099 http://dx.doi.org/10.1007/s00401-013-1105-x |
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