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Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase non-receptor 14

Protein tyrosine phosphatase non-receptor type 14 (PTPN14) is frequently mutated in a variety of human cancers. However, the cell signaling pathways regulated by PTPN14 largely remain to be elucidated. Here, we identify a list of potential substrates of PTPN14 using a phospho-proteomic approach. We...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Guo, Ailan, Possemato, Anthony, Wang, Chao, Beard, Lydia, Carlin, Cathleen, Markowitz, Sanford D., Polakiewicz, Roberto D., Wang, Zhenghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631434/
https://www.ncbi.nlm.nih.gov/pubmed/22710723
http://dx.doi.org/10.1038/onc.2012.220