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T-Cell Reconstitution after Thymus Xenotransplantation Induces Hair Depigmentation and Loss

Here we present a mouse model for T-cell targeting of hair follicles, linking the pathogenesis of alopecia to that of depigmentation disorders. Clinically, thymus transplantation has been successfully used to treat T-cell immunodeficiency in congenital athymia, but is associated with autoimmunity. W...

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Detalles Bibliográficos
Autores principales: Furmanski, Anna L, O'Shaughnessy, Ryan F L, Saldana, Jose Ignacio, Blundell, Michael P, Thrasher, Adrian J, Sebire, Neil J, Davies, E Graham, Crompton, Tessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631608/
https://www.ncbi.nlm.nih.gov/pubmed/23303453
http://dx.doi.org/10.1038/jid.2012.492