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Degradation of initiator tRNA(Met) by Xrn1/2 via its accumulation in the nucleus of heat-treated HeLa cells

Stress response mechanisms that modulate the dynamics of tRNA degradation and accumulation from the cytoplasm to the nucleus have been studied in yeast, the rat hepatoma and human cells. In the current study, we investigated tRNA degradation and accumulation in HeLa cells under various forms of stre...

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Detalles Bibliográficos
Autores principales: Watanabe, Kazunori, Miyagawa, Ryu, Tomikawa, Chie, Mizuno, Rie, Takahashi, Akihisa, Hori, Hiroyuki, Ijiri, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632136/
https://www.ncbi.nlm.nih.gov/pubmed/23471000
http://dx.doi.org/10.1093/nar/gkt153