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Degradation of initiator tRNA(Met) by Xrn1/2 via its accumulation in the nucleus of heat-treated HeLa cells
Stress response mechanisms that modulate the dynamics of tRNA degradation and accumulation from the cytoplasm to the nucleus have been studied in yeast, the rat hepatoma and human cells. In the current study, we investigated tRNA degradation and accumulation in HeLa cells under various forms of stre...
Autores principales: | Watanabe, Kazunori, Miyagawa, Ryu, Tomikawa, Chie, Mizuno, Rie, Takahashi, Akihisa, Hori, Hiroyuki, Ijiri, Kenichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632136/ https://www.ncbi.nlm.nih.gov/pubmed/23471000 http://dx.doi.org/10.1093/nar/gkt153 |
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