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Nuclear actin levels as an important transcriptional switch

Nuclear actin levels have recently been linked to different cellular fates, suggesting that actin could act as a switch between altered transcriptional states. Here we discuss our latest results on the mechanisms by which nuclear actin levels are regulated and their implications to the functional si...

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Detalles Bibliográficos
Autores principales: Huet, Guillaume, Skarp, Kari-Pekka, Vartiainen, Maria K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632617/
https://www.ncbi.nlm.nih.gov/pubmed/22771994
http://dx.doi.org/10.4161/trns.21062
Descripción
Sumario:Nuclear actin levels have recently been linked to different cellular fates, suggesting that actin could act as a switch between altered transcriptional states. Here we discuss our latest results on the mechanisms by which nuclear actin levels are regulated and their implications to the functional significance of nuclear actin.